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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
11.5 DPC

11 matching records from 11 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Irx2  Iroquois homeobox 2   (Synonyms: IRX6)
Results  Reference
1*J:64020 Christoffels VM, Keijser AG, Houweling AC, Clout DE, Moorman AF, Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart. Dev Biol. 2000 Aug 15;224(2):263-74
1*J:61328 Cohen DR, Cheng CW, Cheng SH, Hui C, Expression of two novel mouse iroquois homeobox genes during neurogenesis. Mech Dev. 2000 Mar 1;91(1-2):317-21
1J:244992 Gomez-Velazquez M, Badia-Careaga C, Lechuga-Vieco AV, Nieto-Arellano R, Tena JJ, Rollan I, Alvarez A, Torroja C, Caceres EF, Roy AR, Galjart N, Delgado-Olguin P, Sanchez-Cabo F, Enriquez JA, Gomez-Skarmeta JL, Manzanares M, CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart. PLoS Genet. 2017 Aug;13(8):e1006985
1J:162637 Hang CT, Yang J, Han P, Cheng HL, Shang C, Ashley E, Zhou B, Chang CP, Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature. 2010 Jul 1;466(7302):62-7
1*J:71423 Houweling AC, Dildrop R, Peters T, Mummenhoff J, Moorman AF, Ruther U, Christoffels VM, Gene and cluster-specific expression of the Iroquois family members during mouse development. Mech Dev. 2001 Sep;107(1-2):169-74
1J:338900 Huang R, Zhang C, Zheng Y, Zhang W, Huang H, Qiu M, Li J, Li F, ISL1 regulates lung branching morphogenesis via Shh signaling pathway. J Biol Chem. 2023 Jul 11;299(8):105034
1J:152142 Koshiba-Takeuchi K, Mori AD, Kaynak BL, Cebra-Thomas J, Sukonnik T, Georges RO, Latham S, Beck L, Henkelman RM, Black BL, Olson EN, Wade J, Takeuchi JK, Nemer M, Gilbert SF, Bruneau BG, Reptilian heart development and the molecular basis of cardiac chamber evolution. Nature. 2009 Sep 3;461(7260):95-8
1J:290226 Kuwahara A, Lewis AE, Coombes C, Leung FS, Percharde M, Bush JO, Delineating the early transcriptional specification of the mammalian trachea and esophagus. Elife. 2020 Jun 9;9:e55526
1J:336866 Puelles L, Hidalgo-Sanchez M, The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer. Int J Mol Sci. 2023 Jun 5;24(11)
1*J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1J:244253 Vincentz JW, Toolan KP, Zhang W, Firulli AB, Hand factor ablation causes defective left ventricular chamber development and compromised adult cardiac function. PLoS Genet. 2017 Jul;13(7):e1006922

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory